Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM392168'
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Phenex Pharmaceuticals AG

Curated by ChEMBL
LigandPNGBDBM392168(US10301272, Example 20 | trans-3-(4-(Cyclohexylmet...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inverse agonist activity at human GAL4 DBD-fused RORgammat LBD (237 to 497 residues) expressed in HEK293T cells assessed as reduction in ROR mediated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FPCPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Phenex Pharmaceuticals AG

Curated by ChEMBL
LigandPNGBDBM392168(US10301272, Example 20 | trans-3-(4-(Cyclohexylmet...)copy SMILEScopy InChI
Affinity DataKd:  0.220nMAssay Description:Binding affinity to recombinant human RORgamma LBD (237 to 497 residues) expressed in Escherichia coli BL21 (DE3) GOLD by 1,8-ANS dye-based thermoflu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FPCPubMed