Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM493606'
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM493606(US10988445, Example 202)copy SMILEScopy InChI
Affinity DataIC50: 7.94nMAssay Description:The assay was run in black 384 well plates (Greiner cat no: 784900). Various concentrations of test ligands in 0.1 microlitres DMSO were dispensed to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BG2S35US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM493606(US10988445, Example 202)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inverse agonist activity at human RORC2 assessed as inhibition of SRC1-derived coactivator peptide by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19BGPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM493606(US10988445, Example 202)copy SMILEScopy InChI
Affinity DataIC50: 31.6nMAssay Description:The scintillation proximity assay (SPA) was run in white polystyrene flat-bottom 384-well plates (Greiner, cat. No. 781075). Assays were carried out ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BG2S35US Patent