Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM50369064'
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50369064(CHEMBL4165905)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]-2-(4-(ethylsulfonyl)phenyl)-N-(4-(2-(methoxymethyl)phenyl)thiophen-2-yl)acetamide from purified N-(HN)6-GST-TCS-human RORgammat ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0WFQPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50369064(CHEMBL4165905)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inverse agonist activity at biotinylated HN-Avi-MBP-TCS-human RORgammat (258 to 518 residues) assessed as inhibition of biotinylated SRC-1 peptide NC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0WFQPubMed