Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM386208'
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386208(N-((2R,3S)-2-(((cis-4- phenylcyclohexyl)oxy)methyl...)copy SMILEScopy InChI
Affinity DataEC50:  2.30nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z321Z2US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386208(N-((2R,3S)-2-(((cis-4- phenylcyclohexyl)oxy)methyl...)copy SMILEScopy InChI
Affinity DataEC50:  11nMAssay Description:Agonist activity at human OX2R expressed in CHO-K1 cells by FLIPR calcium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0ZTSPubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386208(N-((2R,3S)-2-(((cis-4- phenylcyclohexyl)oxy)methyl...)copy SMILEScopy InChI
Affinity DataEC50:  2.30nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CZ3BCWUS Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM386208(N-((2R,3S)-2-(((cis-4- phenylcyclohexyl)oxy)methyl...)copy SMILEScopy InChI
Affinity DataEC50:  2.30nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29S1TD1US Patent