Found 5 Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-alpha' and Ligand = 'BDBM50177010' TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H]TO901317 from LXRalpha ligand binding domain (unknown origin) after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Binding affinity to human LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataEC50: 205nMAssay Description:Agonist activity at human LXRalpha coexpressed in African green monkey CV1 cells by Gal4 responsive reporter gene assayMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataEC50: 205nMAssay Description:Agonist activity at human LXRalpha ligand binding domain(167 to 447 residues) transfected in HEK293 cells after 16 hrs by Gal4-luciferase reporter ge...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataEC50: 19nMAssay Description:Binding affinity to human LXRalphaMore data for this Ligand-Target Pair
