Found 3 Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-beta' and Ligand = 'BDBM50177019' TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Displacement of [3H]TO901317 from LXRbeta ligand binding domain (unknown origin) after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Vitae Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataEC50: 503nMAssay Description:Agonist activity at human LXRbeta ligand binding domain(155 to 460 residues) transfected in HEK293 cells after 16 hrs by Gal4-luciferase reporter gen...More data for this Ligand-Target Pair
