Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM50277548'
TargetP2X purinoceptor 7(Mus musculus)
Instituto de Tecnologia em F£rmacos

Curated by ChEMBL
LigandPNGBDBM50277548(CHEMBL4173394)copy SMILEScopy InChI
Affinity DataIC50: 109nMAssay Description:Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced current at holding potential of -60 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3HWCPubMed
TargetP2X purinoceptor 7(Mus musculus)
Instituto de Tecnologia em F£rmacos

Curated by ChEMBL
LigandPNGBDBM50277548(CHEMBL4173394)copy SMILEScopy InChI
Affinity DataIC50: 343nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3HWCPubMed
TargetP2X purinoceptor 7(Mus musculus)
Instituto de Tecnologia em F£rmacos

Curated by ChEMBL
LigandPNGBDBM50277548(CHEMBL4173394)copy SMILEScopy InChI
Affinity DataIC50: 407nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3HWCPubMed
TargetP2X purinoceptor 7(Mus musculus)
Instituto de Tecnologia em F£rmacos

Curated by ChEMBL
LigandPNGBDBM50277548(CHEMBL4173394)copy SMILEScopy InChI
Affinity DataIC50: 432nMAssay Description:Compound was evaluated to inactivate the bacterial AdoMet-DC; value ranges from 3.8 to 39.6 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3HWCPubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Instituto Oswaldo Cruz

Curated by ChEMBL
LigandPNGBDBM50277548(CHEMBL4173394)copy SMILEScopy InChI
Affinity DataIC50: 536nMAssay Description:Antagonist activity at human P2X7R expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake preincubated for 10 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6V7KPubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Instituto Oswaldo Cruz

Curated by ChEMBL
LigandPNGBDBM50277548(CHEMBL4173394)copy SMILEScopy InChI
Affinity DataIC50: 552nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3HWCPubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Instituto Oswaldo Cruz

Curated by ChEMBL
LigandPNGBDBM50277548(CHEMBL4173394)copy SMILEScopy InChI
Affinity DataIC50: 1.37E+3nMAssay Description:Antagonist activity at human P2X7R expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake preincubated for 5 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58QS8PubMed
TargetP2X purinoceptor 7(Mus musculus)
Instituto de Tecnologia em F£rmacos

Curated by ChEMBL
LigandPNGBDBM50277548(CHEMBL4173394)copy SMILEScopy InChI
Affinity DataIC50: 1.52E+4nMAssay Description:Antagonist activity at P2X7R in Swiss Webster mouse peritoneal macrophages assessed as inhibition of ATP-induced propidium iodide uptake preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6V7KPubMed