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Found 46 Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor gamma' and Ligand = 'BDBM50103521'

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

Ki: 62nMAssay Description:Binding affinity to PPARgamma (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q26113MHPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

Ki: 96nMAssay Description:Binding affinity to PPAR-gamma (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2VX0M6TPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

Ki: 300nMMore data for this Ligand-Target Pair

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PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

Ki: 300nMMore data for this Ligand-Target Pair

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PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

Ki: 340nMAssay Description:Binding affinity to PPARgamma (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2930XSXPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

Ki: 420nMAssay Description:Displacement of fluormone PanPPAR green tracer ligand from human 6His-tagged PPARgamma isoform 1 LBD (203 to 477 residues) expressed in Escherichia c...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2TH8R5MPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2TH8R5MPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

Ki: 600nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2G44VDKPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

Ki: 1.23E+3nMAssay Description:Binding affinity against Peroxisome proliferator activated receptor gamma (PPAR gamma)More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2FN15FGPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

IC50: 720nMAssay Description:Agonist activity at PPARgamma (unknown origin)More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2HT2R3RPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

IC50: 1.70E+3nMAssay Description:Displacement of FITC-NCoR1 peptide from human 6His-tagged PPARgamma isoform 1 LBD (203 to 477 residues) expressed in Escherichia coli BL21(DE3) after...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2TH8R5MPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2TH8R5MPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

IC50: 1.79E+3nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2XD14DJPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

IC50: 2.20E+4nMAssay Description:Transrepression activity at human PPARgamma expressed in HEK293 cells assessed as inhibition of TNFalpha induced NF-kappaB promoter activity pretreat...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2251MKDPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 1.40E+3nMAssay Description:Transactivation of Gal4-fused human PPARgamma transfected in COS7 cells co-transfected with pGAL5-TK-pGL3 and pRennilla-CMV incubated for 39 hrs by d...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2ZS30XGPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 970nMAssay Description:Agonist activity at PPARgamma (unknown origin)More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2DJ5JXGPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

Kd: 871nMAssay Description:Binding affinity to human 6His-tagged PPARgamma LBD expressed in Escherichia coli BL21(DE3) using FITC-NTKNHPMLMNLLKDNPAQD peptide by isothermal titr...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2TH8R5MPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 250nMAssay Description:Transactivation of full length human PPARgamma2 expressed in HEK293T cells co-expressing PPRE after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2TH8R5MPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 260nMAssay Description:Activation of human 6His-tagged PPARgamma isoform 1 LBD (203 to 477 residues) expressed in Escherichia coli BL21(DE3) assessed as increase in FITC-TR...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2TH8R5MPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2TH8R5MPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2TH8R5MPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 350nMAssay Description:Transactivation of chimeric Gal4 yeast DBD fused-PPARgamma LBD (unknown origin) expressed in HEK293T cells co-expressing PPRE after 18 hrs by lucifer...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2TH8R5MPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2TH8R5MPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2TH8R5MPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 1.60E+3nMAssay Description:Agonist activity at human PPARgammaDEF receptor expressed in african green monkey COS7 cells transfected with pGal5-TK-pGL3/pRenilla-CMV assessed as ...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2QV3R8KPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 6.70E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2G44VDKPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 200nMMore data for this Ligand-Target Pair

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PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 3.30E+3nMMore data for this Ligand-Target Pair

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PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 3.50E+3nMMore data for this Ligand-Target Pair

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PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 900nMMore data for this Ligand-Target Pair

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PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 1.77E+4nMMore data for this Ligand-Target Pair

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PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 600nMAssay Description:Transactivation activity at Homo sapiens (human) PPARgammaMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q22Z18FDDrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 98nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2XD14DJPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 2.05E+3nMAssay Description:Transactivation of GAL4-fused human PPARgamma transfected in HEK293BENA cells after 24 hrs by steady glo-luciferase reporter gene assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q29K4DXVPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 4.63E+3nMAssay Description:Agonist activity of the enantiomers of 5-({p-[2-(5-ethyl-2-pyridyl)ethoxy]phenyl} methyl)-(5-2H)-1,3-thiazolidine-2,4-dione at the peroxisome prolife...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2P2728KUS Patent DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 100nMAssay Description:Transactivation of human full length PPARgamma expressed in HEK293 cells after 18 hrs by luciferase reporter gene based luminescence assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2CZ39VRPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 240nMAssay Description:Agonist activity at PPARgamma in human HepG2 cells assessed as activation of PPRE incubated for 24 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2HH6NQ0PubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 1.10E+3nMAssay Description:Transactivation activity at Gal4 fused full length human PPARgamma LBD expressed in HEK293 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2251MKDPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 4.63E+3nMAssay Description:Agonist activity of the enantiomers of 5-({p-[2-(5-ethyl-2-pyridyl)ethoxy]phenyl}methyl)-(5-2H)-1,3-thiazolidine-2,4-dione at the peroxisome prolifer...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q29025WWUS Patent DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 380nMAssay Description:Transactivation of Gal4 fused human PPARgamma LBD expressed in African green monkey COS7 cells after 42 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2N87D1BPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 589nMAssay Description:Transcriptional activation of peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2FN15FGPubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 500nMAssay Description:Transactivation of GAL4-fused human PPARgamma ligand binding domain expressed in African green monkey COS7 cells after 42 hrs by dual luciferase repo...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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KEGG MMDB PC cid PC sid PDB Similars

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BindingDB Entry DOI: 10.7270/Q2K939G4PubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 1.60E+3nMAssay Description:Displacement of Fluoromone from GST-tagged recombinant human PPARgamma ligand binding domain by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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KEGG MMDB PC cid PC sid PDB Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2K939G4PubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 320nMAssay Description:Transactivation at Gal4 fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells after 42 hrs by luciferase assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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KEGG MMDB PC cid PC sid PDB Similars

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BindingDB Entry DOI: 10.7270/Q26D5W08PubMed DrugBank
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 390nMMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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KEGG MMDB PC cid PC sid PDB Similars

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PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL

BDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)copy SMILEScopy InChI

EC50: 200nMAssay Description:Transactivation of human PPARgamma expressed in African green monkey COS7 cells incubated overnight by dual-glo luciferase reporter gene assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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KEGG MMDB PC cid PC sid PDB Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2348N8DPubMed DrugBank
PDB

3D Structure (crystal)

Targets 1 ▿
- Peroxisome proliferator-activated receptor gamma 46
Publications 16 ▿
- J Med Chem 62: 2008-2023 (2019) 12
- Eur J Med Chem 124: 49-62 (2016) 2
- Bioorg Med Chem Lett 9: 3329-34 (2000) 2
- Bioorg Med Chem 26: 5870-5884 (2018) 2
- Bioorg Med Chem Lett 27: 2776-2780 (2017) 2
- J Med Chem 63: 5031-5073 (2020) 1
- Eur J Med Chem 185: (2020) 1
- Eur J Med Chem 124: 138-152 (2016) 1
- Bioorg Med Chem Lett 25: 2907-12 (2015) 1
- J Nat Prod 82: 259-264 (2019) 1
- Bioorg Med Chem 26: 4153-4167 (2018) 1
- J Med Chem 61: 10067-10083 (2018) 1
- US Patent US10188639 (2019) 1
- Eur J Med Chem 126: 590-603 (2017) 1
- J Med Chem 59: 61-81 (2016) 1
- J Nat Prod 81: 2419-2428 (2018) 1
Institutions 14 ▿
- [The Scripps Research Institute] 12
- [University of Innsbruck] 4
- [SPTanis PharmaChem Consulting LLC, The University of Tokyo, Glaxo Wellcome Research and Development] 2
- [SPTanis PharmaChem Consulting LLC, The University of Tokyo, Glaxo Wellcome Research and Development] 2
- [SPTanis PharmaChem Consulting LLC, The University of Tokyo, Glaxo Wellcome Research and Development] 2
- [DeuteRx, LLC, Genentech, Terns Pharmaceuticals, Goethe-University Frankfurt, Southwest University, Fuji Research Park, R&D Division, Vienna University of Technology, Universit£t Innsbruck, Seoul National University] 1
- [DeuteRx, LLC, Genentech, Terns Pharmaceuticals, Goethe-University Frankfurt, Southwest University, Fuji Research Park, R&D Division, Vienna University of Technology, Universit£t Innsbruck, Seoul National University] 1
- [DeuteRx, LLC, Genentech, Terns Pharmaceuticals, Goethe-University Frankfurt, Southwest University, Fuji Research Park, R&D Division, Vienna University of Technology, Universit£t Innsbruck, Seoul National University] 1
- [DeuteRx, LLC, Genentech, Terns Pharmaceuticals, Goethe-University Frankfurt, Southwest University, Fuji Research Park, R&D Division, Vienna University of Technology, Universit£t Innsbruck, Seoul National University] 1
- [DeuteRx, LLC, Genentech, Terns Pharmaceuticals, Goethe-University Frankfurt, Southwest University, Fuji Research Park, R&D Division, Vienna University of Technology, Universit£t Innsbruck, Seoul National University] 1
- [DeuteRx, LLC, Genentech, Terns Pharmaceuticals, Goethe-University Frankfurt, Southwest University, Fuji Research Park, R&D Division, Vienna University of Technology, Universit£t Innsbruck, Seoul National University] 1
- [DeuteRx, LLC, Genentech, Terns Pharmaceuticals, Goethe-University Frankfurt, Southwest University, Fuji Research Park, R&D Division, Vienna University of Technology, Universit£t Innsbruck, Seoul National University] 1
- [DeuteRx, LLC, Genentech, Terns Pharmaceuticals, Goethe-University Frankfurt, Southwest University, Fuji Research Park, R&D Division, Vienna University of Technology, Universit£t Innsbruck, Seoul National University] 1
- [DeuteRx, LLC, Genentech, Terns Pharmaceuticals, Goethe-University Frankfurt, Southwest University, Fuji Research Park, R&D Division, Vienna University of Technology, Universit£t Innsbruck, Seoul National University] 1
Affinity: 62 to 2.2E+4 nM▿
- Ki 9
- IC50 5
- Kd 2
- EC50 30
- Affinity ≤ nM
Xtal structures: 1
Docked structures: 0
Catalog Cmpds: 1