Found 7 Enz. Inhib. hit(s) with Target = 'Phosphatidylcholine:ceramide cholinephosphotransferase 2' and Ligand = 'BDBM50282224' TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited
Curated by ChEMBL
Takeda Pharmaceutical Company Limited
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase obtained from humanMore data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited
Curated by ChEMBL
Takeda Pharmaceutical Company Limited
Curated by ChEMBL
Affinity DataKd: 240nMAssay Description:Binding affinity to full length C-terminal FLAG tagged human SMS2 S217A mutant expressed in HEK293 cells after 120 mins by AS/MS analysisMore data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited
Curated by ChEMBL
Takeda Pharmaceutical Company Limited
Curated by ChEMBL
Affinity DataKd: >3.00E+3nMAssay Description:Binding affinity to full length C-terminal FLAG tagged human SMS2 S227A mutant expressed in HEK293 cells after 120 mins by AS/MS analysisMore data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited
Curated by ChEMBL
Takeda Pharmaceutical Company Limited
Curated by ChEMBL
Affinity DataKd: 30nMAssay Description:Binding affinity to full length C-terminal FLAG tagged human SMS2 H272A mutant expressed in HEK293 cells after 120 mins by AS/MS analysisMore data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited
Curated by ChEMBL
Takeda Pharmaceutical Company Limited
Curated by ChEMBL
Affinity DataKd: 28nMAssay Description:Kinetic constant was measured for Protein Methylase II of Leishmania donovani promastigotes using supernatant (S12) fractionMore data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited
Curated by ChEMBL
Takeda Pharmaceutical Company Limited
Curated by ChEMBL
Affinity DataKd: 38nMAssay Description:Binding affinity to full length C-terminal FLAG tagged human SMS2 expressed in HEK293 cells after 120 mins by AS/MS analysisMore data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited
Curated by ChEMBL
Takeda Pharmaceutical Company Limited
Curated by ChEMBL
Affinity DataKd: >3.00E+3nMAssay Description:Binding affinity to full length C-terminal FLAG tagged human SMS2 H229A mutant expressed in HEK293 cells after 120 mins by AS/MS analysisMore data for this Ligand-Target Pair
