Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2' and Ligand = 'BDBM50088360'
LigandPNGBDBM50088360(2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one | 2,...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of 2-FAM-InsP5 binding to human SHIP2 catalytic domain (419 to 832 residues) assessed as change in polarization by fluorescence polarizati...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CZMPubMed
LigandPNGBDBM50088360(2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one | 2,...)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human SHIP2 catalytic domain (419 to 832 residues) phosphatase activity assessed as inhibition of Ins(1,3,4,5)P4 production using Ins(1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CZMPubMed
LigandPNGBDBM50088360(2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one | 2,...)copy SMILEScopy InChI
Affinity DataIC50: 8.90E+4nMAssay Description:Inhibition of human SHIP2 catalytic domain (419 to 832 residues) phosphatase activity assessed as phosphate release using Ins(1,3,4,5)P4 as substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CZMPubMed