Found 3 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50365517' TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO). C/Melchor Fern£ndez Almagro 3
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO). C/Melchor Fern£ndez Almagro 3
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Inhibition of human PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO). C/Melchor Fern£ndez Almagro 3
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO). C/Melchor Fern£ndez Almagro 3
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (CNIO). C/Melchor Fern£ndez Almagro 3
Curated by ChEMBL
Spanish National Cancer Research Centre (CNIO). C/Melchor Fern£ndez Almagro 3
Curated by ChEMBL
Affinity DataEC50: 114nMAssay Description:Inhibition of PI3K p110alpha/p85alpha-mediated AKT1 phosphorylation at Ser473 in human U2OS cellsMore data for this Ligand-Target Pair
