Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase regulatory subunit beta' and Ligand = 'BDBM368625'
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Homo sapiens (Human))
Sapienza Universitāadi Roma

LigandPNGBDBM368625(US10227350, Compound 113 | US10227350, Compound 11...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NP26Q2US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Homo sapiens (Human))
Sapienza Universitāadi Roma

LigandPNGBDBM368625(US10227350, Compound 113 | US10227350, Compound 11...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NP26Q2US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Homo sapiens (Human))
Sapienza Universitāadi Roma

LigandPNGBDBM368625(US10227350, Compound 113 | US10227350, Compound 11...)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NP26Q2US Patent