Found 3 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50388102' TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre
Curated by ChEMBL
Spanish National Cancer Research Centre
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Inhibition of human PI3Kalpha by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre
Curated by ChEMBL
Spanish National Cancer Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PI3Kalpha assessed as accumulation of ADPMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre
Curated by ChEMBL
Spanish National Cancer Research Centre
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of PI3Kalpha-mediated AKT phosphorylation at Ser473 in human U2OS cells by Western blot analysisMore data for this Ligand-Target Pair
