Found 3 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM50232450' TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb Company
US Patent
Bristol-Myers Squibb Company
US Patent
Affinity DataIC50: 4nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb Company
US Patent
Bristol-Myers Squibb Company
US Patent
Affinity DataIC50: 4.5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb Company
US Patent
Bristol-Myers Squibb Company
US Patent
Affinity DataIC50: 81nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as suppression of CD69 expression incubated for 60 minsMore data for this Ligand-Target Pair
