Found 2 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM50239117' TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca
Curated by ChEMBL
AstraZeneca
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Inhibition of recombinant human PI3Kdelta using PIP2 as substrate preincubated for 20 mins followed by substrate addition measured after 80 mins in p...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca
Curated by ChEMBL
AstraZeneca
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of PI3Kdelta in human JeKo1 B cells assessed as decrease in AKT phosphorylation at Ser473 measured after 1 hrMore data for this Ligand-Target Pair
