Found 8 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM50380363' TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
University of Basel
Curated by ChEMBL
University of Basel
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
University of Basel
Curated by ChEMBL
University of Basel
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate measured after 2 hrs by ADP-glo plus luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
University of Basel
Curated by ChEMBL
University of Basel
Curated by ChEMBL
Affinity DataIC50: 116nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
University of Basel
Curated by ChEMBL
University of Basel
Curated by ChEMBL
Affinity DataIC50: 116nMAssay Description:Inhibition of PI3K p110delta subunit using [gamma33P]ATP by filter binding assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
University of Basel
Curated by ChEMBL
University of Basel
Curated by ChEMBL
Affinity DataIC50: 116nMAssay Description:Inhibition of PI3K p110delta (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
University of Basel
Curated by ChEMBL
University of Basel
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Antagonist activity was determined against beta-1 adrenergic receptor in spontaneously beating rat atriaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
University of Basel
Curated by ChEMBL
University of Basel
Curated by ChEMBL
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
University of Basel
Curated by ChEMBL
University of Basel
Curated by ChEMBL
Affinity DataKd: 260nMAssay Description:Binding affinity to human PI3Kdelta (R108 to Q1044 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair
