Found 3 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform' and Ligand = 'BDBM50389387' TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome Ltd
Curated by ChEMBL
Cellzome Ltd
Curated by ChEMBL
Affinity DataIC50: 251nMAssay Description:Inhibition of PI3Kgamma by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome Ltd
Curated by ChEMBL
Cellzome Ltd
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of C5a-induced AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome Ltd
Curated by ChEMBL
Cellzome Ltd
Curated by ChEMBL
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of fMLP-induced neutrophil migration assay by cell based assayMore data for this Ligand-Target Pair
