Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Plasma kallikrein' and Ligand = 'BDBM416946'
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416946((+-)-1-(3-(aminomethyl)phenyl)-N-(3-(3-cyclopropyl...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates (DiaPharma Group, Inc., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HM5US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416946((+-)-1-(3-(aminomethyl)phenyl)-N-(3-(3-cyclopropyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416946((+-)-1-(3-(aminomethyl)phenyl)-N-(3-(3-cyclopropyl...)copy SMILEScopy InChI
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416946((+-)-1-(3-(aminomethyl)phenyl)-N-(3-(3-cyclopropyl...)copy SMILEScopy InChI
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416946((+-)-1-(3-(aminomethyl)phenyl)-N-(3-(3-cyclopropyl...)copy SMILEScopy InChI
Affinity DataIC50: 56nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416946((+-)-1-(3-(aminomethyl)phenyl)-N-(3-(3-cyclopropyl...)copy SMILEScopy InChI
Affinity DataIC50: 191nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416946((+-)-1-(3-(aminomethyl)phenyl)-N-(3-(3-cyclopropyl...)copy SMILEScopy InChI
Affinity DataIC50: 191nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed