Compile Data Set for Download or QSAR
Found 19 Enz. Inhib. hit(s) with Target = 'Plasma kallikrein' and Ligand = 'BDBM416993'
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates (DiaPharma Group, Inc., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HM5US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates (DiaPharma Group, Inc., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26Q218GUS Patent
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4PXV
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4PXV
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J1078D
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates (DiaPharma Group, Inc., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26Q218GUS Patent
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates. In these experiments, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6FXHUS Patent
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates. In these experiments, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6FXHUS Patent
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates (DiaPharma Group, Inc., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HM5CNFUS Patent
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates (DiaPharma Group, Inc., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HM5CNFUS Patent
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:Plasma kallikrein activity assay. The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC862HUS Patent
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:Plasma kallikrein activity assay. The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC862HUS Patent
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates (DiaPharma Group, Inc., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8Q7SUS Patent
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates (DiaPharma Group, Inc., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8Q7SUS Patent
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J1078D
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed
TargetPlasma kallikrein(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM416993((+)-N-(5-(1-amino-1-(4-cyanophenyl)-3-cyclopropylp...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB572SPubMed