Found 10 Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM13535' TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasmaMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasmaMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of PDGFR beta (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of wild type Platelet-derived growth factor receptor beta phosphorylation in CHO cellsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human PDGFR-beta (557 to end residues) using EAIYAAPFAKKK as substrate after 10 mins in presence of ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKd: 4.5nMAssay Description:Binding constant for PDGFRB kinase domainMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKd: 4.5nMAssay Description:Binding constant for PDGFRB kinase domainMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKd: 7.80nMAssay Description:Average Binding Constant for PDGFRB; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKd: 4.5nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKd: 4.5nMAssay Description:Binding affinity to PDGFRBMore data for this Ligand-Target Pair
