Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM138324'
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138324(US8877944, 28)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM138324(US8877944, 28)copy SMILEScopy InChI
Affinity DataKd:  34nMAssay Description:Binding affinity to full length recombinant human PARP-1 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4ZKFPubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Nerviano Medical Sciences S.R.L.

US Patent
LigandPNGBDBM138324(US8877944, 28)copy SMILEScopy InChI
Affinity DataKd:  34nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PBMUS Patent