Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM167427'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167427(US9073893, 65)copy SMILEScopy InChI
Affinity DataIC50: 44nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NERVIANO MEDICAL SCIENCES S.R.L.

US Patent
LigandPNGBDBM167427(US9073893, 65)copy SMILEScopy InChI
Affinity DataKd:  11nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1C52US Patent