Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM27501'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27501(1,5-dihydroxyisoquinoline | CHEMBL338314 | ISQ | i...)copy SMILEScopy InChI
Affinity DataIC50: 151nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27501(1,5-dihydroxyisoquinoline | CHEMBL338314 | ISQ | i...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:The compound was tested for poly(ADP-ribose)polymerase (PARP) inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B857DNPubMed