Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM27708'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Fujisawa Pharmaceutical Co. Ltd

LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Fujisawa Pharmaceutical Co. Ltd

LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0KQ6PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Fujisawa Pharmaceutical Co. Ltd

LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q23ZZ3PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Fujisawa Pharmaceutical Co. Ltd

LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant PARP1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53KPWPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Fujisawa Pharmaceutical Co. Ltd

LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JF0PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Fujisawa Pharmaceutical Co. Ltd

LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 65nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03D7JPubMed