Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM27709'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM27709(2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Bos taurus)TBA
LigandPNGBDBM27709(2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin...)copy SMILEScopy InChI
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM27709(2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM27709(2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin...)copy SMILEScopy InChI
Affinity DataIC50: 16nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair