Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM27716'
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM27716(4-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:In vitro inhibitory concentration against Poly(ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NDPPubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM27716(4-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of human recombinant PARP1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53KPWPubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM27716(4-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 120nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed