Found 2 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM50145139' TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
BioMarin Pharmaceutical Inc.
Curated by ChEMBL
BioMarin Pharmaceutical Inc.
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human PARP1 using [3H]NAD as substrate after 1 min by microplate scintillation counting analysisMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
BioMarin Pharmaceutical Inc.
Curated by ChEMBL
BioMarin Pharmaceutical Inc.
Curated by ChEMBL
Affinity DataEC50: 149nMAssay Description:Inhibition of PARP in human LoVo cells assessed as inhibition of poly(ADP)-ribose polymerization for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
