Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM50445952'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Universit£ di Milano

Curated by ChEMBL
LigandPNGBDBM50445952(CHEMBL3105886)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human GST-fused PARP-1 expressed in Escherichia coli after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9RX4PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Universit£ di Milano

Curated by ChEMBL
LigandPNGBDBM50445952(CHEMBL3105886)copy SMILEScopy InChI
Affinity DataEC50:  400nMAssay Description:Inhibition of PARP-1 in human HeLa cells assessed as decrease of H2O2-induced PARylation after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9RX4PubMed