Found 5 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 2' and Ligand = 'BDBM50188594' TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Health& Science University
Curated by ChEMBL
Health& Science University
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of full length recombinant human His6-tagged PARP2 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Health& Science University
Curated by ChEMBL
Health& Science University
Curated by ChEMBL
Affinity DataIC50: 114nMAssay Description:Inhibition of recombinant human His6-tagged PARP2 autophosphorylation at ADP-ribosyltransferase domain by LC-MS/MS methodMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Health& Science University
Curated by ChEMBL
Health& Science University
Curated by ChEMBL
Affinity DataIC50: 114nMAssay Description:Effect on IP3 turnover by phospholipaseC positively linked to human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Health& Science University
Curated by ChEMBL
Health& Science University
Curated by ChEMBL
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Health& Science University
Curated by ChEMBL
Health& Science University
Curated by ChEMBL
Affinity DataIC50: 5.01E+3nMAssay Description:Binding affinity to PARP2 in human Jurkat cell extract after 45 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
