Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-1' and Ligand = 'BDBM50250875'
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Leibniz-Forschungsinstitut f�r Molekulare Pharmakologie (FMP)

Curated by ChEMBL
LigandPNGBDBM50250875(CHEMBL4095003)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human 6xHis-tagged TNKS1 ART domain (1030 to 1317 residues) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GXGPubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Leibniz-Forschungsinstitut f�r Molekulare Pharmakologie (FMP)

Curated by ChEMBL
LigandPNGBDBM50250875(CHEMBL4095003)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of human TNKS1 (1030 to 1317 residues) measured after 20 hrs in presence of NAD+ by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22SXPubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Leibniz-Forschungsinstitut f�r Molekulare Pharmakologie (FMP)

Curated by ChEMBL
LigandPNGBDBM50250875(CHEMBL4095003)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human 6xHis-tagged TNKS1 ART domain (1030 to 1317 residues) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GXGPubMed