Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-2' and Ligand = 'BDBM50505333'
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare KGaA

Curated by ChEMBL
LigandPNGBDBM50505333(CHEMBL4437173)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of GST-tagged recombinant human TNKS2 (667 to 1166 end residues) expressed in baculovirus infected sf9 cells using biotinylated substrate ...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare KGaA

Curated by ChEMBL
LigandPNGBDBM50505333(CHEMBL4437173)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Effect on IP3 turnover by phospholipaseC positively linked to human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare KGaA

Curated by ChEMBL
LigandPNGBDBM50505333(CHEMBL4437173)copy SMILEScopy InChI
Affinity DataIC50: 9.20nMMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Healthcare KGaA

Curated by ChEMBL
LigandPNGBDBM50505333(CHEMBL4437173)copy SMILEScopy InChI
Affinity DataIC50: 9.20nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS2 (873 to 1166 residues) expressed in baculovirus infected sf9 cells assessed ...More data for this Ligand-Target Pair