Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Polycomb protein EED' and Ligand = 'BDBM291873'
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291873(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:To assess the compounds potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total of tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291873(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent
TargetPolycomb protein EED(Homo sapiens (Human))TBA
LigandPNGBDBM291873(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Representative compounds of the present disclosure were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29W0JNHUS Patent