Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Polycomb protein EED' and Ligand = 'BDBM50235644'
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50235644(CHEMBL4065766)copy SMILEScopy InChI
Affinity DataKi:  0.740nMAssay Description:In vitro displacement of [3H]-LY 278584 from rat cerebral cortex 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7QQGPubMed
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50235644(CHEMBL4065766)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of EED in human OCILY19 cells assessed as reduction in H3K27 trymethylation measured after 6 days by alphaLISA methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7QQGPubMed
TargetPolycomb protein EED(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50235644(CHEMBL4065766)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of EED in human G401 cells assessed as reduction in H3K27 trymethylation measured after 6 days by alphaLISA methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7QQGPubMed