Found 5 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50078850' TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of Naples
Curated by ChEMBL
University of Naples
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of Naples
Curated by ChEMBL
University of Naples
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human 5-LOX by cell free assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of Naples
Curated by ChEMBL
University of Naples
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of human 5-LOX by intact cell based assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of Naples
Curated by ChEMBL
University of Naples
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of Naples
Curated by ChEMBL
University of Naples
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr...More data for this Ligand-Target Pair
