Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50078883'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of Naples

Curated by ChEMBL
LigandPNGBDBM50078883(CHEMBL3416365)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72K5HPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of Naples

Curated by ChEMBL
LigandPNGBDBM50078883(CHEMBL3416365)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72K5HPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of Naples

Curated by ChEMBL
LigandPNGBDBM50078883(CHEMBL3416365)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72K5HPubMed