Found 4 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid lipoxygenase ALOX12' and Ligand = 'BDBM50350396' TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of 12-lipoxygenase in human platelets assessed as reduction of PAR1-AP-induced 12 HETE production by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Mus musculus)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of mouse N-terminally His6-tagged 12-lipoxygenase expressed in SF9 insect cells assessed as 12-HPETE formation using arachidonic acid by U...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human platelet-type N-terminally His6-tagged 12-lipoxygenase assessed as conjugated diene product formation using arachidonic acid by U...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human platelet-type N-terminally His6-tagged 12-lipoxygenase assessed as conjugated diene product formation using arachidonic acid by U...More data for this Ligand-Target Pair
