Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM35254'
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)copy SMILEScopy InChI
Affinity DataKi:  3.60E+4nMAssay Description:Binding affinity to human ERG expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GSDPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)copy SMILEScopy InChI
Affinity DataKi:  3.60E+4nMAssay Description:Binding affinity to human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P60QPPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 181nMAssay Description:Inhibition of human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9J4NPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 182nMAssay Description:Inhibitory concentration against potassium channel HERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1S7CPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 182nMAssay Description:Inhibition of human ERG expressed in CHO cells by whole cell patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8T25PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 182nMAssay Description:Inhibition of human Potassium channel HERG expressed in mammalian cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ2BGZPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 229nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ052WPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 231nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6DT2PubMed