Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM50341448'
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50341448(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Displacement of labeled dofetilide human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z2ZPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50341448(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]-Dofetilide from recombinant human ERG expressed in CHOK1 cell membranes incubated for 4 hrs under dark condition by luminescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS300CPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50341448(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4RQCPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50341448(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in CHOK1 cell membranes incubated for 4 hrs in dark by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B8QPubMed