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Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM50483771'
Target
Presenilin-1
(Homo sapiens (Human))
Pfizer Inc.
Curated by
ChEMBL
Ligand
BDBM50483771
(CHEMBL1770914)
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Affinity Data
IC50: 4.60nM
Assay Description:
Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2FF3W75
PubMed