Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Procathepsin L' and Ligand = 'BDBM19855'
TargetProcathepsin L(Homo sapiens (Human))
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM19855(Balicatib | CHEMBL371064 | N-[1-(cyanomethylcarbam...)copy SMILEScopy InChI
Affinity DataKi:  503nMAssay Description:Inhibition of human cathepsin-L using Z-Phe-Arg-AMC as substrate preincubated for 30 mins measured after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1F44PubMed
TargetProcathepsin L(Homo sapiens (Human))
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM19855(Balicatib | CHEMBL371064 | N-[1-(cyanomethylcarbam...)copy SMILEScopy InChI
Affinity DataKi:  3.26E+3nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-pNA chromogenic substrate fluorogenic substrate incubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P11NTPubMed
TargetProcathepsin L(Homo sapiens (Human))
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM19855(Balicatib | CHEMBL371064 | N-[1-(cyanomethylcarbam...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of cathepsin L in human HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9BM2PubMed
TargetProcathepsin L(Homo sapiens (Human))
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM19855(Balicatib | CHEMBL371064 | N-[1-(cyanomethylcarbam...)copy SMILEScopy InChI
Affinity DataIC50: 503nM EC50:  48nMpH: 5.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4N63PubMed