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Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) with Target = 'Procathepsin L [114-333,T223A]' and Ligand = 'BDBM31992'
Target
Procathepsin L [114-333,T223A]
(Homo sapiens (Human))
AstraZeneca
Ligand
BDBM31992
(Dipeptidyl nitrile inhibitor, 25)
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Affinity Data
IC50: 13nM
pH: 7.0 T: 2°C
Assay Description:
IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
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Ligand Info
Purchase
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2TT4PBM
PubMed