Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Prolyl endopeptidase' and Ligand = 'BDBM50135630'
TargetProlyl endopeptidase(Homo sapiens (Human))
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135630((S)-2-[(S)-2-(5-Phenyl-isoxazole-3-carbonyl)-pyrro...)copy SMILEScopy InChI
Affinity DataKi:  1.87nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8D9KPubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135630((S)-2-[(S)-2-(5-Phenyl-isoxazole-3-carbonyl)-pyrro...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8D9KPubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135630((S)-2-[(S)-2-(5-Phenyl-isoxazole-3-carbonyl)-pyrro...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Inhibition of human prolyl endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9BNHPubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135630((S)-2-[(S)-2-(5-Phenyl-isoxazole-3-carbonyl)-pyrro...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8D9KPubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135630((S)-2-[(S)-2-(5-Phenyl-isoxazole-3-carbonyl)-pyrro...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (PO) in human; Moderately activeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8D9KPubMed