Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with Target = 'Prolyl endopeptidase' and Ligand = 'BDBM50393843'
TargetProlyl endopeptidase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Inhibition of human POP expressed in Escherichia coli BL21 pre-incubated for 30 mins before ZGP-pNA substrate additionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89FBBPubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Inhibition of recombinant human POP assessed as affinity constant of second step of inhibition pre-incubated for 2 hrs before addition of ZGP-pNA sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB5682PubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Inhibition of recombinant human POP pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB5682PubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of POP in human HCEC cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CHFPubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of POP in human LN229 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CHFPubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of POP in human LNZ308 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CHFPubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibition of POP in human LN18 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CHFPubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of POP in intact human LNZ308 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CHFPubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of POP in intact human LN18 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CHFPubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibition of POP in intact human LN229 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CHFPubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of POP in intact human HCEC cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CHFPubMed