Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Prolyl endopeptidase' and Ligand = 'BDBM50434161'
TargetProlyl endopeptidase(Homo sapiens (Human))
University of Antwerp (UA)

Curated by ChEMBL
LigandPNGBDBM50434161(CHEMBL2385275 | US9346814, Cmpd No 10 Example 13)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant PREP expressed in Escherichia coli using Z-Gly-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP83J7PubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
University of Antwerp (UA)

Curated by ChEMBL
LigandPNGBDBM50434161(CHEMBL2385275 | US9346814, Cmpd No 10 Example 13)copy SMILEScopy InChI
Affinity DataIC50: 360nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37V6DUS Patent