Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Prolyl endopeptidase FAP' and Ligand = 'BDBM50009366'
TargetProlyl endopeptidase FAP(Mus musculus (Mouse))
Universiteit Antwerp; Fox Chase Cancer Center

US Patent
LigandPNGBDBM50009366(CHEMBL3233842 | US11504364, Compound Ref.-Comp. | ...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37V6DUS Patent
TargetProlyl endopeptidase FAP(Mus musculus (Mouse))
Universiteit Antwerp; Fox Chase Cancer Center

US Patent
LigandPNGBDBM50009366(CHEMBL3233842 | US11504364, Compound Ref.-Comp. | ...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84DFWPubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))TBA
LigandPNGBDBM50009366(CHEMBL3233842 | US11504364, Compound Ref.-Comp. | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:FAPα enzymatic exopeptidase (dipeptidase) activity assay. To assay baseline FAPa enzymatic exopeptidase activity, 40 ng of recombinant human FAP...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XS607BUS Patent
TargetProlyl endopeptidase FAP(Homo sapiens (Human))TBA
LigandPNGBDBM50009366(CHEMBL3233842 | US11504364, Compound Ref.-Comp. | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:FAPα enzymatic exopeptidase (dipeptidase) activity assay. To assay baseline FAPa enzymatic exopeptidase activity, 40 ng of recombinant human FAP...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XS607BUS Patent