Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Prostaglandin D2 receptor 2' and Ligand = 'BDBM50339749'
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
AstraZeneca R& D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339749((S)-2-(2-((4-(benzylsulfonyl)-3-methylpiperazin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RQJPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
AstraZeneca R& D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339749((S)-2-(2-((4-(benzylsulfonyl)-3-methylpiperazin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as inhibition of PGD2-mediated Ca2+ fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RQJPubMed