Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Prostaglandin E synthase' and Ligand = 'BDBM50271083'
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer Inc. St. Louis Laboratory

Curated by ChEMBL
LigandPNGBDBM50271083(5-(5-bromo-2-(2-chloro-6-fluorophenyl)-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of mPGES1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X292VPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer Inc. St. Louis Laboratory

Curated by ChEMBL
LigandPNGBDBM50271083(5-(5-bromo-2-(2-chloro-6-fluorophenyl)-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human mPGES-1 expressed in human 293E cell microsomes using PGH2 as substrate assessed as PGE2 production after 2.5 mins by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3FQ0PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Pfizer Inc. St. Louis Laboratory

Curated by ChEMBL
LigandPNGBDBM50271083(5-(5-bromo-2-(2-chloro-6-fluorophenyl)-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 3.94E+3nMAssay Description:Inhibition of purified mPGES-1 (1 to 152) (unknown origin) extracted from detergent-solubilized baculovirus-infected insect Sf9 cell membranes using ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3FQ0PubMed