Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50156547'
TargetProstaglandin E2 receptor EP4 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50156547(4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542P2GPubMed
TargetProstaglandin E2 receptor EP4 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50156547(4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZT2PubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
EMD-Serono Research Institute, Inc.

Curated by ChEMBL
LigandPNGBDBM50156547(4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Displacement of [3H]PGE4 from human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W096SWPubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
EMD-Serono Research Institute, Inc.

Curated by ChEMBL
LigandPNGBDBM50156547(4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Binding affinity to human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BBQPubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
EMD-Serono Research Institute, Inc.

Curated by ChEMBL
LigandPNGBDBM50156547(4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...)copy SMILEScopy InChI
Affinity DataEC50:  0.0200nMAssay Description:Agonist activity at human EP4 receptor by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W096SWPubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50156547(4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...)copy SMILEScopy InChI
Affinity DataEC50:  3.10nMAssay Description:Agonist activity at rat EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542P2GPubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
EMD-Serono Research Institute, Inc.

Curated by ChEMBL
LigandPNGBDBM50156547(4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrroli...)copy SMILEScopy InChI
Affinity DataEC50:  11nMAssay Description:Functional activity at human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BBQPubMed