Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1' and Ligand = 'BDBM17636'
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 2.23E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of recombinant COX1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95JQPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H133CXPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University of Torino

Curated by ChEMBL
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Thromboxane (TXA2) receptor antagonist activity using human plateletMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed