Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50049024'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049024(4-[6-(4-Fluoro-phenyl)-spiro[2.4]hept-5-en-5-yl]-b...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity of the compound against prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9Q6MPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049024(4-[6-(4-Fluoro-phenyl)-spiro[2.4]hept-5-en-5-yl]-b...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D21WTXPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049024(4-[6-(4-Fluoro-phenyl)-spiro[2.4]hept-5-en-5-yl]-b...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Compound was evaluated in vitro for the inhibitory activity against inducible form of human recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26Z3Q
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049024(4-[6-(4-Fluoro-phenyl)-spiro[2.4]hept-5-en-5-yl]-b...)copy SMILEScopy InChI
Affinity DataIC50: 3.02nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736S4DPubMed